Last week we told you to start regular bench players Felix Jones (96 yards, TD) and Steve Breaston (seven catches, 77 yards) and they both performed like starters in the flex spot. However, the biggest piece of advice we gave you was telling you to start DeAngelo Williams, who broke out against KC for 148 total yards and three TDs. As a rule, players that have good matchups, are hot, getting a chance because of injury, or at least assured touches are always useful for the flex spot and as bye-week or injury replacements.

Every week owners are put to the test with the critical decisions in the flex spot that can determine the outcome of your game. If you have guys like RB Willis McGahee facing the awful Colts run defense or WRs Bobby Engram and Reggie Brown who are starting to hit their strides after coming back from injury, feel comfortable putting them, among the eight others below, into the flex slot in Week 6.
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After Week 1 was complete, many NFL teams saw big-name guys go down. Some are gone for the season, altering the 2008 landscape permanently. Others are harboring smaller bumps and bruises affecting their status for only a week or two.
 
Below are the 10 injuries to guys not named Brady or Colston that will have the greatest impact on the fantasy world in Week 2. Obviously a lost season from the NFL’s poster boy and 4-6 weeks without Drew Brees’ No. 1 wideout have clear and lasting impacts. However, there are quite a few more that can affect fantasy owners’ decision-making for Week 2. Read more »